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Pathogénie tuberculeuse et nouvelles cibles thérapeutiques
2010 - Veyron-Churlet R., I. Zanella-Cléon, M. Cohen-Gonsaud, V. Molle, and L. Kremer.
Phosphorylation of the Mycobacterium tuberculosis -ketoacyl-ACP reductase MabA regulates mycolic acid biosynthesis. J. Biol. Chem. 285 : 12714-12725.
2010 - Rombouts Y., E. Elass, C. Biot, E. Maes, B. Coddeville, A. Burguière, C. Tokarski, E. Buisine, X. Trivelli, L. Kremer, and Y. Guerardel.
Structural analysis of an unusual bioactive N-acylated lipooligosaccharide LOS-IV in Mycobacterium marinum. J. Am. Chem. Soc. 132 : 16073-16084.
2010 - Ojha A. K., X. Trivelli, Y. Guerardel, L. Kremer, and G. F. Hatfull.
Enzymatic hydrolysis of trehalose dimycolate releases free mycolic acid during mycobacterial growth in biofilms. J. Biol. Chem. 285 : 17380-17389.
2010 - Molle V., J. Leiba, I. Zanella-Cléon, M. Becchi, and L. Kremer.
An improved method to unravel phosphoacceptors in Ser/Thr protein kinases-phosphorylated substrates. Proteomics. 10 : 3910-3915.
2010 - Molle V. , G. Gulten, C. Vilchèze, R. Veyron-Churlet, I. Zanella-Cléon, J. C. Sacchettini, W. R. Jacobs, Jr., and L. Kremer
Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis. Mol. Microbiol. 78 : 1591-1610.
2010 - Alibaud L. , A. Alahari, X. Trivelli, A. K. Ojha, G. F. Hatfull, Y. Guerardel, and L. Kremer.
Temperature-dependent regulation of mycolic acid cyclopropanation in saprophytic mycobacteria : role of the Mycobacterium smegmatis 1351 gene (MSMEG_1351) in cis-cyclopropanation of -mycolates. J. Biol. Chem. 285 : 21698-21707.
2008 - Gratraud P. , N. Surolia, G. Besra, A. Surolia, and L. Kremer.
Antimycobacterial activity and mechanism of action of NAS-91. Antimicrob. Agents Chemother. 52 : 1162-1166.
