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Accueil du site > Publications Scientifiques > Biogenèse membranaire et interactions avec la cellule hôte chez Plasmodium et Toxoplasma

Biogenèse membranaire et interactions avec la cellule hôte chez Plasmodium et Toxoplasma

2011 - Tonkin, Roques, Lamarque, Pugnière, Douguet, Crawford, Lebrun*, Boulanger*.

Host cell invasion by Apicomplexan parasites : Insights from the structure of AMA1 in complex with a RON2 peptide. Science 22 ;333(6041):463-7., *contribution égale

2011 - Tawk, Dubremetz, Montcourrier, Chicanne, Merezegue, Richard, Payrastre, Meissner, Vial, Roy, Wengelnik, M. Lebrun

Phosphatidylinositol 3-monophosphate is involved in Toxoplasma apicoplast biogenesis. Plos Pathogen e1001286

2011 - Lebrun M., M Roques, M Tonkin, M Boulanger

Identification of region of RON2 of Apicomplexan parasites suitable for targeting by vaccines and drugs. European Patent Application. May 6, 2011. EP 11305540.4

2011 - Lamarque, Besteiro, Papoin, Roques, Vulliez-Le Normand, Morlon-Guyot, Dubremetz, Fauquenoy, Tomavo, Faber, Kocken, Thomas, Boulanger, Bentley, and M. Lebrun

The RON2-AMA1 interaction is a critical step in moving junction-dependent invasion by Apicomplexan parasites. Plos Pathogen. e1001276

2011 - Abkarian M, Massiera G, Berry L, Roques M, Braun-Breton C.

A novel mechanism for egress of malarial parasites from red blood cells. Blood. 2011 Apr 14 ;117(15):4118-24.

2010 - Shastri S, Zeeman AM, Berry L, Verburgh RJ, Braun-Breton C, Thomas AW, Gannoun-Zaki L, Kocken CH, Vial HJ.

Plasmodium CDP-DAG synthase : an atypical gene with an essential N-terminal extension. Int J Parasitol. 2010 Sep ;40(11):1257-68.

2009-MS. Breinich, DJP. Ferguson2, BJ. Foth, GG. van Dooren, M Lebrun, DV. Quon, B Striepen, PJ. Bradley, F Frischknecht1, VB. Carruthers and Markus Meissner

An ancestral dynamin is required for the biogenesis of specialised secretory organelles in apicomplexan parasites. Current Biology. 19:277-86.

2009-Besteiro, A Michelin, J Poncet, JF Dubremetz, M. Lebrun

Export of a Toxoplasma gondii rhoptry neck protein complex at the host cell membrane to form the moving junction during invasion. Plos Pathogen. 5(2):e1000309.

2009-AB Ismael, D Hedhli, O Cérède, M Lebrun, I Dimier-Poisson, and MN Mévélec

Further analysis of protection induced by the MIC3 DNA vaccine against T. gondii : CD4 and CD8 T Cells are the major effectors of the MIC3 DNA vaccine-induced protection, both Lectin-like and EGF-like domains of MIC3 conferred protection. Vaccine 14 ;27(22):2959-66

2009 - Saridaki T., Frohlich K.S., Braun Breton C. and Lanzer M.

Export of PfSBP1 to the Plasmodium falciparum Maurer’s clefts. Traffic.10(2) : 137-152

2009 - Michelin, A. ; Bittame, A. ; Bordat, Y. ; Travier, L. ; Mercier, C. ; Dubremetz, J. F. ; Lebrun, M.

GRA12, a Toxoplasma dense granule protein associated with the intravacuolar membranous nanotubular network. Int J Parasitol. (), 39:299-306

2009 - Labesse, G. ; Gelin, M. ; Bessin, Y. ; Lebrun, M. ; Papoin, J. ; Cerdan, R. ; Arold, S. T. ; Dubremetz, J.F.

ROP2 from Toxoplasma gondii : a virulence factor with a protein-kinase fold and no enzymatic activity. Structure. (), 17:139-46

2009 - Labesse G, M Gelin, Y Bessin, M Lebrun, J Papoin, R Cerdan, S Arold, JF Dubremetz

ROP2 from Toxoplasma gondii : A virulence factor with a protein-kinase fold and no enzymatic activity. Structure, 17(1):139-46.

2008 - Vincensini, L., Fall G., Berry L., Blisnick T. and Braun Breton C.

The RhopH complex is transferred to the host cell cytoplasm following red blood cell invasion by Plasmodium falciparum. Mol. Biochem. Parasitol. 160(2) : 81-89

2005 - Lebrun, M. ; Michelin, A. ; El Hajj, H. ; Poncet, J. ; Bradley, P. J ; Vial, H. ; Dubremetz, J. F.

The rhoptry neck protein RON4 re-localizes at the moving junction during Toxoplasma gondii invasion. Cell Microbiol. , 7:1823-33