Berry L, Chen CT, Francia ME, Guerin A, Graindorge A, Saliou JM, Grandmougin M, Wein S, Bechara C, Morlon-Guyot J, Bordat Y, Gubbels MJ, Lebrun M, Dubremetz JF, Daher W. Toxoplasma gondii chromosomal passenger complex is essential for the organization of a functional mitotic spindle: a prerequisite for productive endodyogeny. Cell Mol Life Sci, (2018) Jul 26.

Morlon-Guyot J, El Hajj H, Martin K, Fois A, Carrillo A, Berry L, Burchmore R, Meissner M, Lebrun M, Daher W. A proteomic analysis unravels novel CORVET and HOPS proteins involved in Toxoplasma gondii secretory organelles biogenesis. Cell Microbiol, (2018) 17:e12870.

Wengelnik K, Daher W, Lebrun M. Phosphoinositides and their functions in apicomplexan parasites. Int J Parasitol. (2018) Jun;48(7):493-504.

Lebrun M, Blanchard N. Host-microbe interactions: parasites. Volume 40 December 2017

Guérin A, El Hajj H, Penarete-Vargas D, Besteiro S, Lebrun M. RON4(L1) is a new member of the moving junction complex in Toxoplasma gondii. Sci Rep, (2017) Dec 20;7(1):17907.

Lentini G, El Hajj H, Papoin J, Fall G, Pfaff AW, Tawil N, Braun-Breton C, Lebrun M. Characterization of Toxoplasma DegP, a rhoptry serine protease crucial for lethal infection in mice. PLoS One, (2017) Dec 15;12(12):e0189556.

Frénal K, Dubremetz JF, Lebrun M, Soldati-Favre D. Gliding motility powers invasion and egress in Apicomplexa. Nat Rev Microbiol, (2017) Nov;15(11):645-660.

Guérin A, Corrales RM, Parker ML, Lamarque MH, Jacot D, El Hajj H, Soldati-Favre D, Boulanger MJ, Lebrun M. Efficient invasion by Toxoplasma depends on the subversion of host protein networks. Nat Microbiol, (2017) Oct;2(10):1358-1366.

Miliu A, Lebrun M, Braun-Breton C, Lamarque MH. Shelph2, a bacterial-like phosphatase of the malaria parasite Plasmodium falciparum, is dispensable during asexual blood stage. PLoS One, (2017) Oct 26;12(10):e0187073.

Nguyen HM, El Hajj H, El Hajj R, Tawil N, Berry L, Lebrun M, Bordat Y, Besteiro S. Toxoplasma gondii autophagy-related protein ATG9 is crucial for the survival of parasites in their host. Cell Microbiol, (2016) Jun (19) 6.

Berry L, Chen CT, Reininger L, Carvalho TG, El Hajj H, Morlon-Guyot J, Bordat Y, Lebrun M, Gubbels MJ, Doerig C, Daher W. The conserved apicomplexan Aurora kinase TgArk3 is involved in endodyogeny, duplication rate and parasite virulence. Cell Microbiol, (2016) Aug;18(8):1106-20.

Daher W, Morlon-Guyot J, Alayi TD, Tomavo S, Wengelnik K, Lebrun M. Identification of Toxoplasma TgPH1, a pleckstrin homology domain-containing protein that binds to the phosphoinositide PI(3,5)P2. Mol Biochem Parasitol, (2016) May;207(1):39-44.

Parker ML, Penarete-Vargas DM, Hamilton PT, Guérin A, Dubey JP, Perlman SJ, Spano F, Lebrun M*, Boulanger MJ*. Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA-RON2 pair. PNAS, (2016) Jan 12;113(2):398-403. *equal contribution

Wang K, Peng ED, Huang AS, Xia D, Vermont SJ, Lentini G, Lebrun M, Wastling JM, Bradley PJ. Identification of Novel O-Linked Glycosylated Toxoplasma Proteins by Vicia villosa Lectin Chromatography. PLoS One, (2016) Mar 7;11(3):e0150561.

Delgadillo RF, Parker ML, Lebrun M, Boulanger MJ, Douguet D. Stability of the Plasmodium falciparum AMA1-RON2 Complex Is Governed by the Domain II (DII) Loop. PLoS One, (2016) Jan 5;11(1):e0144764.

Pihan E., Delgadillo RF., Tonkin ML., Pugnière M., Lebrun M., Boulanger MJ., Douguet D. Computational and biophysical approaches to protein-protein interaction inhibition of Plasmodium falciparum AMA1/RON2 complex. J Comput Aided Mol Des, (2015) Jun;29(6):525-39

Rugarabamu G., Marq JB., Guérin A., Lebrun M., Soldati-Favre D. Distinct contribution of Toxoplasma gondii rhomboid proteases 4 and 5 to micronemal protein protease 1 activity during invasion. Mol Microbiol, (2015). Jul;97(2):244-62.

Lentini G., Kong-Hap M., El Hajj H., Francia M., Claudet C., Striepen B., Dubremetz JF., Lebrun M.  Identification and characterization of Toxoplasma SIP, a conserved apicomplexan cytoskeleton protein involved in maintaining the shape, motility and virulence of the parasite. Cell Microbiol, (2015) 17(1):62-78

Morlon-Guyot J., Pastore S., Berry L., Lebrun M., Daher W. Toxoplasma gondii Vps11, a subunit of HOPS and CORVET tethering complexes, is essential for the biogenesis of secretory organelles. Cell Microbiol, (2015) 1157-1178.

Daher W., Morlon-Guyot J., Sheiner L., Lentini G., Berry L., Tawk L., Dubremetz JF., Wengelnik K., Striepen B., Lebrun M.  Lipid kinases are essential for apicoplast homeostasis in Toxoplasma gondii. Cell Microbiol, (2015) 559-578.

Risco-Castillo V., Topçu Selma., Marinach C., Manzon G., Bigorgne A.E., Briquet S., Baudin X., Lebrun M., Dubremetz J.F., and Olivier Silvie.  Malaria Sporozoites Traverse Host Cells within Transient Vacuoles.  Cell Host & Microbes, (2015) Nov 11;18(5):593-603.

Lamarque MH., Roques M., Kong-Hap M., Tonkin ML., Rugarabamu G., Marq JB., Penarete-Vargas DM., Boulanger MJ., Soldati-Favre D., Lebrun M.  Plasticity and redundancy among AMA-RON pairs ensure host cell entry of Toxoplasma parasites. Nat Commun, (2014) Jun 17;5:4098.Morlon-Guyot J., Berry L., Chen CT., Gubbels MJ., Lebrun M., Daher W.  The Toxoplasma gondii calcium-dependent protein kinase 7 is involved in early steps of parasite division and is crucial for parasite survival. Cell Microbiol, (2014) 95-114.

Kong-Hap MA., Mouammine A., Daher W., Berry L., Lebrun M., Dubremetz JF., Besteiro S.  Regulation of ATG8 membrane association by ATG4 in the parasitic protist Toxoplasma gondii. Autophagy, (2013) September ;9(9):1334-48

Tonkin ML., Crawford J., Lebrun ML., Boulanger MJ.  Babesia divergens and Neospora caninum apical membrane antigen 1 structures reveal selectivity and plasticity in apicomplexan parasite host cell invasion. Protein Sci, (2011) Jan;22(1):114-27

De Napoli. M.G., N. de Miguel., Lebrun M., Moreno S.N.J., Angel S.O., Corvi M.M.  N-terminal palmitoylation is required for Toxoplasma gondii HSP20 inner membrane complex localization. Biochimica and Biophysica Acta (BBA) - Molecular Cell Research, (2013) Jun;1833(6):1329-37.

Lebrun, M., Carruthers, V.B., Cesbron-Delauw, M.-F. Toxoplasma Secretory Proteins and their roles in Cell Invasion and Intracellular Survival. in Toxoplasma gondii: The Model Apicomplexan – Perspectives and Methods, Weiss and Kim (Eds), 2nd edition (20013) 265-315.

Dubremetz JF, Lebrun M. Virulence factors of Toxoplasma gondii. Microbes Infect, (2012) Dec;14(15):1403-10.Lamarque MH, Papoin J, Finizio AL, Lentini G, Pfaff AW, Candolfi E, Dubremetz JF, Lebrun M. Identification of a new rhoptry neck complex RON9/RON10 in the Apicomplexa parasite Toxoplasma gondii. PLoS One, (2012);7(3):e32457.

Lamarque MH, Papoin J, Finizio AL, Lentini G, Pfaff AW, Candolfi E, Dubremetz JF, Lebrun M. Identification of a new rhoptry neck complex RON9/RON10 in the Apicomplexa parasite Toxoplasma gondii. PLoS One, (2012);7(3):e32457.

Vulliez-Le Normand B, Tonkin ML, Lamarque MH, Langer S, Hoos S, Roques M, Saul FA, Faber BW, Bentley GA, Boulanger MJ, Lebrun M. Structural and functional insights into the malaria parasite moving junction complex. PLoS Pathog, (2012);8(6):e1002755.

Tawk, L., Dubremetz, J. F., Montcourrier, P., Chicanne, G., Merezegue, F., Richard, V., Payrastre, B., Meissner, M., Vial, H. J., Roy, C., Wengelnik, K., and Lebrun, M. Phosphatidylinositol 3-monophosphate is involved in Toxoplasma apicoplast biogenesis. PLoS Pathog, (2011) 7, e1001286

Besteiro S, Dubremetz JF, Lebrun M. The moving junction of apicomplexan parasites: a key structure for invasion. Cell Microbiol, (2011) Jun;13(6):797-805.  

Lamarque M, Besteiro S, Papoin J, Roques M, Vulliez-Le Normand B, Morlon-Guyot J, Dubremetz JF, Fauquenoy S, Tomavo S, Faber BW, Kocken CH, Thomas  AW, Boulanger MJ, Bentley GA, Lebrun M. The RON2-AMA1 interaction is a critical step in moving junction-dependent invasion by apicomplexan parasites. PLoS Pathog, (2011) Feb 10;7(2):e1001276.

Hajagos BE, Turetzky JM, Peng ED, Cheng SJ, Ryan CM, Souda P, Whitelegge JP, Lebrun M, Dubremetz JF, Bradley PJ. Molecular dissection of novel trafficking and processing of the Toxoplasma gondii rhoptry metalloprotease toxolysin-1. Traffic, (2012) Feb;13(2):292-304.

Tonkin ML, Roques M, Lamarque MH, Pugnière M, Douguet D, Crawford J, Lebrun M*, Boulanger MJ*. Host cell invasion by apicomplexan parasites: insights from the co-structure of AMA1 with a RON2 peptide. Science, (2011) Jul 22;333(6041):463-7. *equal contribution

Mévélec MN, Ducournau C, Bassuny Ismael A, Olivier M, Sèche E, Lebrun M, Bout D, Dimier-Poisson I. Mic1-3 Knockout Toxoplasma gondii is a good candidate for a vaccine against T. gondii-induced abortion in sheep. Vet Res, (2010) Jul-Aug;41(4):49.

Moiré N, Dion S, Lebrun M, Dubremetz JF, Dimier-Poisson I. Mic1-3KO tachyzoite a live attenuated vaccine candidate against toxoplasmosis derived from a type I strain shows features of type II strain. Exp Parasitol, (2009) Oct;123(2):111-7.

AB Ismael, D Hedhli, O Cérède, M Lebrun, I Dimier-Poisson, and MN Mévélec. Further analysis of protection induced by the MIC3 DNA vaccine against T. gondii: CD4 and CD8 T Cells are the major effectors of the MIC3 DNA vaccine-induced protection, both Lectin-like and EGF-like domains of MIC3 conferred protection. Vaccine, (2009) 14;27(22):2959-66

S Besteiro, A Michelin, J Poncet, JF Dubremetz, M Lebrun. Export of a Toxoplasma gondii rhoptry neck protein complex at the host cell membrane to form the moving junction during invasion.  PloS Pathog, (2009) 5(2):e1000309. “Exceptional" by the Faculty of 1000”

MS. Breinich, DJP. Ferguson2, BJ. Foth, GG. van Dooren, M Lebrun, DV. Quon, B Striepen, PJ. Bradley, F Frischknecht1, VB. Carruthers and Markus Meissner. An ancestral dynamin is required for the biogenesis of specialised secretory organelles in apicomplexan parasites. Current Biology, (2009) 19:277-86.

G Labesse, M Gelin, Y Bessin, M Lebrun, J Papoin, R Cerdan, S Arold, JF Dubremetz.  ROP2 from Toxoplasma gondii: A virulence factor with a protein-kinase fold and no enzymatic activity. Structure, (2009) 17(1):139-46.

A Michelin, A Bittame, Y Bordat, L Travier, C Mercier, JF Dubremetz, M Lebrun. GRA12, a Toxoplasma dense granule protein associated with the intravacuolar membranous nanotubular network. Int J Parasitol, (2008) 39:299-306

H El Hajj, J Papoin , O Cérède , N Garcia-Réguet, M Soête, JF Dubremetz  and M Lebrun. Molecular signals in the trafficking of the Toxoplasma gondii protein MIC3 to the micronemes. Eukaryotic Cell, (2008) 7:1019-1028

Besteiro S, J Bertrand-Michel, M Lebrun, H Vial, JF Dubremetz. Lipidomic analysis of Toxoplasma gondii tachyzoites rhoptries: further insights into the role of cholesterol. Biochem J, (2008) 415:87-96

N de Miguel, M Lebrun, A Heaslip, K Hu, CJ. Beckers, M Matrajt, JF Dubremetz, SO. Angel. Toxoplasma gondii Hsp20 is a stripe-arranged chaperone like protein associated with the outer leaflet of the inner membrane complex. Biol Cell, (2008) 100:479-489

El Hajj H, Lebrun M, Arold ST, Vial H, Labesse G, Dubremetz JF. ROP18 is a rhoptry kinase controlling the intracellular proliferation of Toxoplasma gondii. PLoS Pathog, (2007) Feb;3(2):e14.

El Hajj H, Demey E, Poncet J, Lebrun M, Wu B, Galéotti N, Fourmaux MN, Mercereau-Puijalon O, Vial H, Labesse G, Dubremetz JF. The ROP2 family of Toxoplasma gondii rhoptry proteins: proteomic and genomic characterization and molecular modeling. Proteomics, 2006 Nov;6(21):5773-84.

Ismael AB, Dimier-Poisson I, Lebrun M, Dubremetz JF, Bout D, Mevelec MN. Mic1-3 knockout of Toxoplasma gondii is a successful vaccine against chronic and congenital toxoplasmosis in mice. J Infect Dis, (2006) Oct 15;194(8):1176-83.

El Hajj H, Lebrun M, Fourmaux MN, Vial H, Dubremetz JF. Inverted topology of the Toxoplasma gondii ROP5 rhoptry protein provides new insights into the association of the ROP2 protein family with the parasitophorous vacuole membrane. Cell Microbiol, (2007) Jan;9(1):54-64.

Lebrun, M., Carruthers, V.B., Cesbron-Delauw, M.-F. Toxoplasma Secretory Proteins and their roles in Cell Invasion and Intracellular Survival. in Toxoplasma gondii: The Model Apicomplexan – Perspectives and Methods, Weiss and Kim (Eds). 1rst edition (2007) 265-315.

Hajj HE, Lebrun M, Fourmaux MN, Vial H, Dubremetz JF. Characterization, biosynthesis and fate of ROP7, a ROP2 related rhoptry protein of Toxoplasma gondii. Mol Biochem Parasitol, (2006) Mar;146(1):98-100.

O. Cérède, J. F. Dubremetz, M. Soête, D. Deslée, H. Vial, D. Bout, and M. Lebrun. Synergistic role of micronemal proteins in Toxoplasma gondii virulence. J Exp Med, (2005) 201:453-463

O. Cérède, JF Dubremetz, D. Bout, M. Lebrun. 2002. The Toxoplasma gondii protein MIC3 requires pro-peptide cleavage and dimerization to function as adhesin. EMBO J.  21:2526-2536.

D. Bout, MN Mevelec, F Velge-Roussel, I Dimier-Poisson , Lebrun M. Prospects for a human Toxoplasma vaccine. Curr Drug Targets Immune Endocr Metabol Disord, (2002) 2:227-34.

D. Soldati, J. F. Dubremetz and M. Lebrun. Biosynthesis of micronemal proteins and their role in adhesion and invasion by the Apicomplexa. Int J Parasitol, (2001) 31 :1293-12302

M. Lebrun* , N. Garcia-Reguet*, Fourmaux M.N., O. Mercereau-Puijalon, C. Beckers, B. Samyn, J. Van Beemen, D. Bout, and J. F. Dubremetz. The microneme protein MIC3 of Toxoplasma gondii is a secretory adhesin which binds to both the surface of the host cells and the surface of the parasite. Cell Microbiol, (2000) 2:353-364 * Equal contribution

S. Dramsi, P. Dehoux, M. Lebrun, P. Goossens, and P. Cossart. Identification of four new members of Internalin multigene family in Listeria monocytogenes strain EGD. Infect Immun, (1997) 65: 1615-1625.

M. Lebrun, J. Mengaud, H. Ohayon, F. Nato, and P. Cossart. Internalin must be on the bacterial surface to mediate entry of Listeria monocytogenes into epithelial cells. Mol Microbiol, (1996) 21:579-592.

J. Mengaud, M. Lecuit, M. Lebrun, F. Nato, J-C. Mazié, and P. Cossart. Antibodies to the leucine-rich repeat region of internalin block entry of Listeria monocytogenes into cells expressing E-cadherin. Infect Immun, (1996) 64:5430-5433.

S. Dramsi, M. Lebrun, and P. Cossart. Molecular and genetic determinants involved in invasion of Mammalian cells by Listeria monocytogenes. In bacterial Invasivness. Ed. V. L. Miller. Current Topics Microbiology Immunology, (1996) 209:61-77

B. Poutrel, F. B. Gilbert, and M. Lebrun. Effects of cultural conditions on production of type 5 capsular polysaccharide by human and bovine Staphlococcus aureus strains. Clin Diag Lab Immunol, (1995) 2:166-171.

M. Lebrun, A. Audurier, and P. Cossart. Plasmid-borne cadmium resistance genes in Listeria monocytogenes are similar to cadA and cadC of Staphylococcus aureus and are induced by cadmium. J Bacteriol, (1994) 176:3040-3048

M. Lebrun, A. Audurier., and P. Cossart. Plasmid-borne cadmium resistance genes in Listeria monocytogenes are present on Tn5422, a novel transposon closely related to Tn917. J Bacteriol, (1994) 176:3049-3061

M. Lebrun, J. Loulergue, E. Chaslus-Dancla, and A. Audurier. Plasmids in Listeria monocytogenes in relation to cadmium resistance. Applied Env Microbiol, (1992) 58: 3183-3186